Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt84 | 03SK013B2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50I, I72V, Q95H, F100Y, L101I, T112V, T124S, T125A, K136Q, D167E, V201I, K211R, T218I, L234I, R269K, D278A | S283G |
| >03SK013B2| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGHETAYYILKLAGRWPVKVIHTDNGSN FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19T, K20R, E35D, M36I, R41K, D60E, H69K, L89M, I93L |
| >03SK013B2| codons 1-99 PQITLWQRPLVTIKVGGQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, T39E, S48T, K122E, D123N, I135V, S162C, K173A, N175H, D177E, T200A, Q207K, V245Q, A272P, K277R, E291D, V292I, I293V, E298D, G335D, Q336R, E344D, R356K, G359T, A376G, T377L, K390R, A400I, E404D, V435A, E449D, L452I, S468H, D471E, H483Q, L484I, L491S, S519N, K527R, K530R, A534S, A554N | K13R |
| >03SK013B2| codons 1-560 PISPIETVPVKLRPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQHPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEDAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDRWTYQIYQDPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIGLESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRDTKIGKAGYVTDRGRQKVVHLTETTNQKTELQ AIQIALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |