<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt84 03SK013B2 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D25E, V31I, M50I, I72V, Q95H, F100Y, L101I, T112V, T124S, T125A, K136Q, D167E, V201I, K211R, T218I, L234I, R269K, D278A S283G
>03SK013B2| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGHETAYYILKLAGRWPVKVIHTDNGSN
FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19T, K20R, E35D, M36I, R41K, D60E, H69K, L89M, I93L  
>03SK013B2| codons 1-99
PQITLWQRPLVTIKVGGQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, T39E, S48T, K122E, D123N, I135V, S162C, K173A, N175H, D177E, T200A, Q207K, V245Q, A272P, K277R, E291D, V292I, I293V, E298D, G335D, Q336R, E344D, R356K, G359T, A376G, T377L, K390R, A400I, E404D, V435A, E449D, L452I, S468H, D471E, H483Q, L484I, L491S, S519N, K527R, K530R, A534S, A554N K13R
>03SK013B2| codons 1-560
PISPIETVPVKLRPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQHPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEDAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDRWTYQIYQDPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIGLESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRDTKIGKAGYVTDRGRQKVVHLTETTNQKTELQ
AIQIALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKERVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006