Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt39 | 03PS073MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6E, S17N, D25E, V31I, S39N, M50T, F100Y, L101I, T112V, T125A, K136Q, G163E, V201I, I203M, T218I, L234I, A265V, D278A | S283G |
| >03PS073MB1| codons 1-288 FLDGIEKAQEEHEKYHNNWRAMASEFNLPPIVAKEIVANCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIEQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | T12S, I15V, L19I, M36I, N37S, R41K, R57K, D60E, H69K, I85V, L89M, I93L |
| >03PS073MB1| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKLIGGIGGFIKVKQYE QILIEICGKKAIGTVLVGPTPVNIVGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, E36A, T39E, S48T, V118I, K122E, D123S, T165I, K166R, K173T, Q174K, T200A, Q207E, F214L, V245M, D250N, A272P, K275R, T286A, E291D, V292I, I293V, Q334H, R356K, M357V, G359T, V365I, T386I, K390R, E396G, A400T, E404D, V435A, L452I, R461K, V466I, D471E, T477A, E478G, H483Q, L491S, S513G, S519N, K527N, K530R, V531I, A534S, A554R, K558R |
| >03PS073MB1| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIRILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKNSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYAKVRTA HTNDIKQLTEAVQKIATESIVIWGKIPKFRLPIQKGTWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKIGKAGYVTDKGRQKIVSLTETTNQKAGLQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKGESELVNQIIEQLINKERIYLSWVPAHK GIGGNEQVDKLVSRGIRRVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |