Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt158 | 04PS201B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, E13A, D25E, V31I, L45Q, M50I, I72V, F100Y, T112V, T124S, T125A, I135V, K136Q, V201I, K215N, L234I, A265V, D278A | S283G |
| >04PS201B1| codons 1-288 FLDGIDKAQEDHAKYHSNWRAMASEFNLPPIVAKEIVASCDKCQQKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYLLKLAGRWPVKVIHTDNGSN FTSSAVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQNQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19T, K20R, E35D, M36I, R41K, L63T, H69K, L89M, I93L |
| >04PS201B1| codons 1-99 PQITLWQRPLVTIKIGGQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, V60I, K122E, D123G, K166R, K173A, Q174K, D177E, T200A, Q207A, R211K, V245Q, D250E, A272S, K277R, T286A, K287R, E291D, V292I, I293V, P313T, Q334E, G335D, P345S, R356K, M357R, G359T, I375X, T377M, S379C, K390R, A400I, E404D, L452K, V458I, T470S, D471E, H483Q, L491S, S519N, A534S, A554N |
| >04PS201B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGARALTDIVPLTEEAE LELAENREILKETVHGVYYDPSKDLIAEIQKQGEDQWTYQIYQESFKNLKTGKYAKRRTA HTNDVKQLTEAVQKXAMECIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKKGKAGYITDRGRQKVVSLSETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |