Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt42 | 03PS079B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, I72V, I84M, L101I, T112V, T124N, K136Q, D167E, V201I, L234I, A265V, D278A | S283G |
| >03PS079B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L |
| >03PS079B1| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, E6D, V35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, K311R, Q334N, G335D, R356K, G359S, T377L, K390R, A400T, E404D, I411T, I434M, L452I, R461K, S468T, D471E, K476R, H483Y, L491S, S519N, Q524E, K530R, A534S, A554S |
| >03PS079B1| codons 1-560 PISSIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWTPEWEFVNTP PLVKLWYQLEKEPMVGAETFYVDGAANRETKIGKAGYVTDKGRQKVVTLTETTNQRTELQ AIYLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |