Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt223 | 04SK217B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, S24N, D25E, V31I, L74I, T112V, I113V, T124A, T125A, V201I, L234I, V260I | A8V, V281M |
| >04SK217B1| codons 1-288 FLDGIDKVQEDHEKYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVIPRRKAKIIRDYGKQMAGDDCMASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63T, H69K, I93L |
| >04SK217B1| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, K122E, D123E, I135T, K173T, D177E, T200E, Q207E, V245Q, A272P, K277R, L283I, E291D, V292I, I293V, Q334H, G335D, R356K, R358K, G359N, T369A, I375V, T377L, K390R, E404D, N418D, V435A, V466I, V467I, D471E, L491S, I505T, S519N, K527N, K530R, A534S, A554S |
| >04SK217B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHREKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMKNA HTNDVKQLAEAVQKVALESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVDTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKIISLTETTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGTIQAQPDKSESELVNQIIEQLINKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |