Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt217 | 04SK196B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, S57R, I72V, F100Y, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, A205S, T218I, L234I, A265V, R269K, D278A | S283G |
| >04SK196B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCRPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGTN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I47V | T12S, I13X, I15V, L19T, M36I, R41K, H69K, I93L |
| >04SK196B1| codons 1-99 PQITLWQRPLVSXKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMVGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135T, S162C, K173V, Q174K, D177E, T200A, Q207E, R211K, V245E, A272P, E291D, V292L, L325S, Q334D, G335D, R356K, M357R, G359T, T377M, K388R, K390R, A400T, T403S, E404D, I434M, V435A, A437V, E449D, L452M, K454R, R461K, V467I, S468T, D471E, A481T, H483Q, L491S, S519N, I521V, K530R, A534S, A554N | I180T |
| >04SK196B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRVKNPEIVT YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDLIPLTEEAE LELAENREILKEPVHGVYYDPSKDSIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKIAMESIVIWGKTPRFRLPIQKETWETWWSDYWQATWIPEWEFVNTP PLVKLWYQLEKEPMAGVETFYVDGAANRDTKMGRAGYVTDKGRQKVITLTETTNQKTELQ TIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQVIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |