Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt123 | 03SK111B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L68V | D25E, V31I, M50I, I72V, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, D167E, V201I, K211R, K215N, L234I, R269K, D278A | S283G, D286N |
| >03SK111B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHVEGKVILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQNQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQNED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, N37S, R41K, L63V, H69K, L89M, I93L |
| >03SK111B1| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48P, A98S, K122E, D123S, T165I, K173A, T200A, Q207D, R211K, V245Q, E248T, D250E, A272P, K275Q, L283I, R284K, E291D, V292I, I293V, R307G, E308A, Q334H, G335D, T338I, R356K, G359T, V365I, T377R, T386I, K390R, A400T, E404D, K431Q, A437V, L452A, V467I, S468N, D471E, H483Q, L491S, S519N, K530R, A534S, A554S |
| >03SK111B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKIPKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPTKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLIKGTKALTDIVPLTEEAE LELAENGAILKEPVHGVYYDPSKDLIAEIQKQGHDQWIYQIYQEPFKNLKTGKYAKMRTA HTNDIKQLTEAVQKIARESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEQEPIVGVETFYVDGAANRETKAGKAGYVTDRGRQKVINLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |