Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SK-150 | 04SK150B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, L45V, M50I, I72V, I84V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, K219E, L234I, D278A | S283G |
| >04SK150B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQVKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYVEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITEIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, M36I, L63V, H69K, L89M, I93L | F53S |
| >04SK150B1| codons 1-99 PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGSIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, S48T, K122E, D123S, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272R, K277R, T286A, E291D, V292I, I293V, I329V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, A437V, L452I, S468C, T470N, D471E, H483Q, L491S, I495V, S519N, K527Q, K530X, A534S, A554S, K558E | Y144H |
| >04SK150B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRHQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYRGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGVETFYVDGAANRETKIGKAGYVTDRGRQKVVCLNETTNQKTELQ AIQLALQDSGSEVNVVTDSQYALGIIQAQPDKSESELVNQIIEQLIQKEXVYLSWVPAHK GIGGNEQVDKLVSSGIREVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |