Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt110 | 03SK078B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, M50T, I72V, L74I, I84M, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, K215N, T218I, Q221R, L234I, R269K, D278A | S283G |
| >03SK078B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKVIIVAVHVASGYMEAEVIPAETGQDTAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQNQIIKIRNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63H, H69K, I93L |
| >03SK078B1| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIHIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207T, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, Q334E, G335D, R356K, M357R, G359T, K366R, T377L, K390R, A400T, E404D, V435A, E449N, L452T, V466I, D471E, H483Q, L491S, I506L, S519N, Q524E, K530R, A534S, A554N |
| >03SK078B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRTHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVRQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRNTKTGKAGYVTDRGRQKIVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGILQAQPDKSESELVNQIIEELIKKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |