Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt94 | 03SK039B2 | South Africa | 2003 | HIV1 | CRF49_cpx | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, D25E, V31I, M50I, I72V, L74I, L101I, G106A, T112V, I113V, S119T, T124A, T125A, K136Q, I141V, V201I, T218I, L234I, A265V, D270E, D278A | S283G |
| >03SK039B2| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFILKLAARWPVKVVHTDNGTN FTSAAVKAACWWAGIQQEFGVPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIREYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, W42*, C67M, H69K, L89M, I93L |
| >03SK039B2| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGK*KPKMIGGIGGFIKVRQYD QILIEIMGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39K, K43E, S48T, V60I, D121H, K122E, D177E, I178V, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357Q, G359T, T377I, K390R, A400I, E404D, V435A, G436E, L452I, S468T, L469I, D471E, H483Q, L491S, S519N, Q524E, A534S, A554S | D186G |
| >03SK039B2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEVVI YQYMDGLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKQRTA HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAANRETKIGKAGYVTDRGRQKVVTITETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |