<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt87 03SK020B2 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    S17N, S24A, V31I, I72V, I84M, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, R187G, V201I, T218I, L234I, A265V, R269K, D278A  
>03SK020B2| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMAADFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGPN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKGKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, E35D, M36I, N37D, P39Q, R41K, D60E, Q61N, I62V, L63P, H69K, L89M, I93L  
>03SK020B2| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDIDLQGKWKPKMIGGIGGFIKVRQYE
NVPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35K, T39D, S48T, V60I, K122E, S162A, K173A, Q174K, D177G, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, R284G, T286A, E291D, V292I, I293V, D320G, Q334D, G335D, R356K, R358G, G359T, A376S, T377L, K390R, A400I, T403S, E404D, V435A, A437V, L452M, S468T, L469V, D471E, H483Q, L491P, E516G, S519N, K527Q, K530R, A534S, A554S  
>03SK020B2| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICDEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPGIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLGGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYGPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKMGTA
HTNDVKQLTEAVQKISLESIVIWGKTPKFRLPIQKETWEIWWSDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGVETFYVDGAANRETKMGKAGYVTDRGRQKVVTVTETTNQKTELQ
AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESGLVNQIIEQLIQKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006