Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt87 | 03SK020B2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, S24A, V31I, I72V, I84M, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, R187G, V201I, T218I, L234I, A265V, R269K, D278A |
| >03SK020B2| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMAADFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGPN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKGKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, E35D, M36I, N37D, P39Q, R41K, D60E, Q61N, I62V, L63P, H69K, L89M, I93L |
| >03SK020B2| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDIDLQGKWKPKMIGGIGGFIKVRQYE NVPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35K, T39D, S48T, V60I, K122E, S162A, K173A, Q174K, D177G, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D320G, Q334D, G335D, R356K, R358G, G359T, A376S, T377L, K390R, A400I, T403S, E404D, V435A, A437V, L452M, S468T, L469V, D471E, H483Q, L491P, E516G, S519N, K527Q, K530R, A534S, A554S | R284G |
| >03SK020B2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICDEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPGIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLGGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYGPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKMGTA HTNDVKQLTEAVQKISLESIVIWGKTPKFRLPIQKETWEIWWSDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGVETFYVDGAANRETKMGKAGYVTDRGRQKVVTVTETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESGLVNQIIEQLIQKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |