<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt117 03SK097B1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D25E, V31I, M50T, I72V, F100C, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, D207G, T218I, L234I, A265V, R269K, D278A S283G
>03SK097B1| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYCILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATGIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19T, M36I, R41K, D60E, L63S, H69K, I93L  
>03SK097B1| codons 1-99
PQITLWQRPLVTIKIGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QISIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I5V, V35T, E36A, T39D, S48T, K122E, D123G, T165I, K173A, Q174K, D177E, G196E, T200A, I202V, Q207E, V245Q, D250E, A272P, E291D, V292I, I293V, V317A, Q334D, R356K, G359T, K366R, A376S, T377M, K390R, A400T, T403S, E404D, V435A, A437V, K451R, L452I, V467I, D471E, H483Q, L491S, L517I, S519N, K530R, A534S, A554S R78K, Q222R
>03SK097B1| codons 1-560
PISPVETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFKELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIEQHRAKVEELREHLLRWGFTTPDKKHRKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVRQLTEAVQKISMESIVIWGKTPKFRLPIQKETWETWWSDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGVETFYVDGAANRETRIGKAGYVTDRGRQKVISLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006