<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt114 03SK091B1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D25E, V31I, M50I, I72V, P90A, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, A265V, D278A S283G
>03SK091B1| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIAAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V292I, P313S, V317A, Q330L, Q334N, G335D, A355T, R356K, G359S, T377M, K385R, K390R, A400T, E404D, V435A, A437V, L452I, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554K  
>03SK091B1| codons 292-560
IIPLTEEAELELAENREILKESVHGAYYDPSKDLIAEILKQGNDQWTYQIYQEPFKNLKT
GKYTKMRSAHTNDVKQLTEAVQKIAMESIVIWGRTPKFRLPIQKETWETWWTDYWQATWI
PEWEFVNTPPLVKLWYQLEKEPIAGVETFYVDGAANRETKIGKAGYVTDRGRQKIVSLTE
TTNQKTELQAIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERV
YLSWVPAHKGIGGNEQVDKLVSKGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006