Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt89 | 03SK029B2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, V31I, M50I, I72V, L101I, K111Q, T112I, T124A, T125A, K136Q, D167E, Q177L, V201I, L234I, A265V, R269K, D278A | S283G |
| >03SK029B2| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVQIIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVLMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10M, I13V, K14R, L19I, M36I, R41K, I62V, L63V, H69K, T74A, L89M, I93L |
| >03SK029B2| codons 1-99 PQITLWQRPMVTVRIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QVVIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I2T, P4S, V8I, V35K, T39E, S48T, K122E, S162C, K173A, Q174R, D177E, T200E, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, R358K, G359S, E370D, T377M, K390R, E399D, A400T, E404D, E432D, V435I, K454R, R461K, D471E, H483K, L491A, Q507R, K512N, S519N, K527Q, K530R, A534S, A554S |
| >03SK029B2| codons 1-560 PTSSIETIPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPEIVI YQYMDDLYVGSDLEIGQHREKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRKSA HTNDVKQLTDAVQKIAMESIVIWGKTPKFRLPIQKETWDTWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGRAGYVTDKGRQKVVSLTETTNQKTELQ AIKLALQDSGAEVNIVTDSQYALGIIRAQPDNSESELVNQIIEQLIQKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |