Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt88 | 03SK023B2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| R20K, D25E, V31I, M50I, I72V, I84V, Y99H, F100Y, L101I, T112V, T124A, T125A, K136Q, I200V, V201I, T206S, T218I, L234I, A265V, R269K, D278A | S283G |
| >03SK023B2| codons 1-288 FLDGIDKAQEEHEKYHSNWKAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYVEAEVIPAETGQETAHYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERVIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, N37S, R41K, H69K, L89M, I93L |
| >03SK023B2| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y188L | V35T, T39E, S48T, V60I, K122E, D123G, E138G, K166R, K173I, Q174K, D177E, V179T, R211K, V245Q, A272Q, T286A, E291D, V292I, I293V, Q334P, G335D, R356K, G359T, K366R, T377L, K390R, A400R, E404D, V435A, G436E, K451T, V466I, T470S, D471E, T477A, H483Q, L491S, S519N, K530R, A554K | G231R, N306S |
| >03SK023B2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNGTPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEITI YQYMDDLLVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMRYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYQGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAESREILKEPVHGVYYDPSKDLIAEIQKQGPDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIALESIVIWGKTPKFRLPIQKETWERWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAANRETTLGKAGYVTDRGRQKIVSLSETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLAWVPAHK GIGGNEQVDKLVSKGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |