Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA25081 | CA68752 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|RTI | NA |
| 2 | Unknown | 58 |
| 3 | 3TC+LPV+TDF | 35 |
| 4 | FTC+RTV+T20+TDF+TPV | 31 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54M, I84V, L90M | L10I, L19I, K20R, E34D, E35D, M36I, R41K, L63P, A71T, I85V, I93L |
| >CA68752| codons 1-99 PQITLWQRPIVTIKIGGQIREALLDTGADDTVLDDINLPGKWKPKIVGGIGGFMKVRQYD QIPIEICGHKTIGTVLVGPTPVNVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, M184V, T215F | K219Q | V35I, S48T, K122E, I135T, E169D, H208Y, R211K, D218E, L228H |
| >CA68753| codons 1-261 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKEGKITKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQYLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLV |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |