Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8402 | CA68638 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 91 |
| 2 | 3TC+AZT+IDV | 174 |
| 3 | DDI+EFV+LPV | 39 |
| 4 | DDI+EFV+LPV+TDF | 100 |
| 5 | 3TC+APV+DDI+LPV+TDF | 61 |
| 6 | 3TC+APV+DDI+FPV+LPV+TDF | 3 |
| 7 | 3TC+DDI+FPV+LPV+TDF | 49 |
| 8 | FTC+RTV+T20+TDF+TPV | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33F, T74P | L10I, I13V, N37ND, I62V, L63P, I93L |
| >CA68638| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKLIGGIGGFVKVRQYD QVPIEICGHKAIGPVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74LV, M184V, T215Y | K103N | E6D, V35VL, T39TA, S68SG, A98AS, I142V, V179VI, T200TA, I202IV, E203Q, Q207D, A272P, R284K, T286A, I293V |
| >CA68639| codons 1-301 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAELEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIGQHRAKVQELRDHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |