<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1340 CA68608 U.S. 2006 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA
2 Unknown 496

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V L10F, L24I, G73C I13V, K20I, M36I, D60E, L63P, I64V, I66V, A71T, I72T, T91S  
>CA68608| codons 1-99
PQITLWQRPFVTVKIGGQLIEALIDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYE
QIPVEVCGHKTTCTVLVGPTPVNVIGRNLLSQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y V75M, K219KE G190A K101H E28K, K32E, V35T, T39K, K43E, K49R, V60I, V118I, K122E, T139TAS, S162SDGN, I178F, G196E, T200K, L205F, Q207E, H208Y, L228H, Q242L, A272P, A288AS, I293V, E297A  
>CA68609| codons 1-301
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICKELEEEGKISRIGPENPYNTPI
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNESPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDFVI
YQYVDDLYVASDLEIEQHRKKIEEFREYLWRWGFYTPDEKHQKEPPFHWMGYELHPDKWT
VLPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVVPLTAEAE
L

References
Author Title Citation
Rhee, SY HIV-1 protease mutations and protease inhibitor cross resistance. AAC, 2010