Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1340 | CA68608 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
| 2 | Unknown | 496 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V | L10F, L24I, G73C | I13V, K20I, M36I, D60E, L63P, I64V, I66V, A71T, I72T, T91S |
| >CA68608| codons 1-99 PQITLWQRPFVTVKIGGQLIEALIDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYE QIPVEVCGHKTTCTVLVGPTPVNVIGRNLLSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | K219KE | G190A | K101H | E28K, K32E, V35T, T39K, K43E, K49R, V60I, V118I, K122E, T139TAS, S162SDGN, I178F, G196E, T200K, L205F, Q207E, H208Y, L228H, Q242L, A272P, A288AS, I293V, E297A |
| >CA68609| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICKELEEEGKISRIGPENPYNTPI FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNESPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDFVI YQYVDDLYVASDLEIEQHRKKIEEFREYLWRWGFYTPDEKHQKEPPFHWMGYELHPDKWT VLPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |