Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3914 | CA68560 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 111 |
| 2 | AZT+DDC | 39 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+D4T | 37 |
| 5 | AZT+DDI+NFV | 77 |
| 6 | 3TC+AZT+EFV+NFV | 91 |
| 7 | APV+D4T+DDI | 31 |
| 8 | ABC+APV+D4T+DDI+LPV | 61 |
| 9 | ABC+DDI+TDF | 78 |
| 10 | 3TC+AZT+DDI+LPV+TDF | 100 |
| 11 | ATV+AZT+FTC+RTV+TDF | 47 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, M46I, L90M | G73GC, T74P | L10LI, L33M, R41K, K43KR, I62V, L63P, C67CF, A71IT, I72V, V77I, I93L |
| >CA68560| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTIMEEMNLPGKWRPKIIGGIGGFIKVRQYD QVPIEIFGHKTVCPVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69DN, K70R, M184V | D67G, K219Q | Y188L | A98G | K64R, I142V, G196E, R211A, F214L, V245T, K275R, Q278E, I293V, E297K |
| >CA68561| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKGSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLLVGSDLEIEQHRTKIEELRQHLLAWGLTTPDQKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIRVKELCKLLRGTKALTEVVPLTKEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |