<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ACTG303_3553 3553RT_f1 U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 2
2 AZT+DDI 160
3 3TC+AZT+DDI 48

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215F V75M, K219W   V108I K20R, V35M, T39A, V60I, T69TA, L109I, V118I, K122E, I135T, S162D, K166R, T200TI, I202V, D218E, V245Q, A272P, E291D  
>3553RT_f1| codons 1-303
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSARWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTIIDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTRILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRIKVEELRQHLLRWGFFTPEWKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVIPLTEEAE
LEL

References
Author Title Citation
Albrecht, M Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine. ARHR, 2000