<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ACTG302_1521 1521RT_f1 U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 DDI 148
2 3TC+AZT+DDI 47

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, M184V, T215Y       I31L, K49R, K102R, V118I, K122R, V245M, E297K, E300ED L301LV, E302E*
>1521RT_f1| codons 20-302
KVKQWPLTEEKLKALVEICTEMEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKVVDFRE
LNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSIPLDRDFRKYTAFTIPSINNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHR
TKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIMLPEKDSWTVNDIQK
LVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTKEADV*

References
Author Title Citation
Katzenstein, DA Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection. ARHR, 2001