Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt233 | 1134MB | South Africa | 1999 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11I | T12S, I15V, L19T, E35D, M36I, R41K, K45R, L63P, H69K, V82I, L89I, I93L |
| >1134MB| codons 1-99 PQITLWQRPLISIKVGGQTKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPINIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75A | K20R, V35T, E36A, T39D, S48T, K104R, K122E, D123S, I135T, K166R, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, D324N, Q334H, G335D, R356K, G359T, A376G, T377L, K385R, T386I, K390R, A400I, E404D, V435A, L452I, R461K, R463K, T470S, D471E, T477A, H483Q, L491S, S519N, K530R, A534S, A554K |
| >1134MB| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLADFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKNLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIGLESIVIWGRIPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKIGKAGYVTDKGKQKVVSLSETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |