Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt195 | 04SK164B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12S, I15V, G16E, L19I, M36I, N37S, R41K, L63S, H69K, I93L |
| >04SK164B1| codons 1-99 PQITLWQRPVVSIKVEGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T27S, V35T, T39Q, E40D, S48T, K122E, D123S, K173A, Q197L, T200E, E204Q, Q207D, R211K, D218G, V245Q, E248T, A272P, K277R, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K385R, K390R, A400T, E404D, E432D, I434M, V435I, A437V, V467I, D471E, H483L, L491S, S519N, K527N, A534S, A554T |
| >04SK164B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICQDMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIVI YQYMDDLYVGSDLEIGLHREKIEQLRDHLLKWGFTTPGKKHQKEPPFLWMGYELHPDKWT VQPIQLPTKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGRTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPMIGVETFYVDGAANRETKLGKAGYVTDRGRQKVISLTETTNQKTELQ AILLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKVYLSWVPAHK GIGGNEQVDKLVSTGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, M50T, I72V, F100Y, L101I, T112V, T125A, K136Q, D167E, V201I, L234I, R269K, D278A | S283G |
| >04SK164B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |