Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt171 | 04SK052MB2 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, R41K, D60E, L63I, H69K, L89M, I93L |
| >04SK052MB2| codons 1-99 PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE QIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123S, I135T, T165I, K166R, K173T, Q174K, V179I, G196E, T200A, Q207E, F214L, E233G, A272S, T286A, E291D, V292I, I293V, Q334H, R356K, G359T, V365I, K390R, E396G, A400T, E404D, V435A, A437V, L452I, R461Q, V466I, D471E, T477A, Q480H, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554K |
| >04SK052MB2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIRILEPFRTKNPDIII YQYMDDLYVGSDLEIEQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYGLHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKGTWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGVETFYVDGAANRETKIGKAGYVTDQGRQKIVSLTETTNQKAELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERIYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6E, E10D, D25E, K34R, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, D278A | S283G |
| >04SK052MB2| codons 1-288 FLDGIEKAQDEHEKYHSNWRAMASEFNLPPVVAREIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |