Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt168 | 04PS284B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39K, S48T, V60I, K122E, D123G, I142V, S162A, K173A, D177G, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P313T, V317A, G333E, Q334N, R356K, M357K, G359T, I375V, T377L, K390R, A400R, E404D, V435A, G436E, V467I, S468T, L469I, D471E, H483Q, L491S, E492K, S519N, K527N, A534S, A554K, K558R |
| >04PS284B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPGIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKETVHGAYYDPSKDLIAEIQKQENGQWTYQIYQEPFKNLKTGKYAKKRTA HTNDVKQLTEAVQKVALESIVIWGKTPKFRLPIQKETWERWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAANRETKLGKAGYVTDRGRQKVITITETTNQKTELQ AIQLALQDSGSKVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKVYLSWVPAHK GIGGNEQVDKLVSKGIRRVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19I, E35D, M36I, R41K, L63T, H69K, L89M, I93L |
| >04PS284B1| codons 1-99 PQITLWQRPLVTIRVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50I, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, D167E, V201I, T206S, T218I, L234I, R269K, D278A | S283G |
| >04PS284B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGPN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |