Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt160 | 04PS204B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, V60I, V118I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, A272K, K277R, K281R, T286A, E291D, V292I, I293V, Q334D, G335D, R356K, G359T, A371V, T377M, K388R, K390R, A400T, E404D, E413G, V435A, G436E, L452I, V466I, V467I, S468T, T470S, D471E, H483Q, L491S, S519N, K530R, A534S, A554S | N306D |
| >04PS204B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYKGIKVRQLCRLLRGAKALTDIVPLTEEAE LELAEDREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEVVQKIAMESIVIWGKTPRFRLPIQKETWETWWTDYWQATWIPGWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAANRETKIGKAGYVTDRGRQKIITLSETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, K14R, I15V, L19M, M36I, R41K, L63P, H69K, L89M, I93L |
| >04PS204B1| codons 1-99 PQITLWQRPLVAIRVGGQMKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, V31I, K34R, M50I, T112V, T124N, T125A, K136Q, M178V, V201I, T218I, L234I, A265V, D278A, D279G | S283G |
| >04PS204B1| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPIVAREIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSNAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQVAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGAGCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |