<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt159 04PS202B1 South Africa 2004 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, E35D, M36L, N37D, R41K, L63P, I64M, H69K, L89M, I93L  
>04PS202B1| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDLDLPGKWKPKMIGGIGGFIKVRQYD
QIPMEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, S48T, W88C, K101R, K122E, D123N, I135R, E169K, K173A, D177E, T200A, I202T, Q207K, R211K, W212*, F214L, V245Q, S251H, A272P, K275R, K277R, E291D, V292I, I293V, Q334E, A355T, R356K, M357L, G359T, V365I, K366R, T377M, S379G, K390R, A400T, E404D, V435A, E449D, V458I, V466I, V467I, D471E, H483Y, L491S, E492K, S519N, K527N, K530R, A534S, A554R  
>04PS202B1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILKPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKTEELRKHLLK*GLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDHWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYTKLRTA
HTNDIRQLTEAVQKIAMEGIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRDTKLGKAGYITDRGRQKIISLTETTNQKTELQ
AIYLALQDSGSKVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERVYLSWVPAHK
GIGGNEQVDKLVSRGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006