Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt153 | 04PS194MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, E36A, T39E, S48T, W88C, V118I, K122E, D123S, T165I, K166R, K173A, Q174K, V179I, T200A, Q207E, F214L, V245E, A272S, K275Q, T286A, E291D, V292I, I293V, Q334Y, R356K, G359A, V365I, K390R, E396G, E404D, K431Q, V435A, A437V, Y441C, L452M, R461K, V466I, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554K | I180T |
| >04PS194MB1| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIRILEPFRAKNPDIIT YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYSGIQVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYGQWTYQIYQEPFKNLKTGKYAKMRAA HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKGTWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEQEPIAGVETFCVDGAANRETKMGKAGYVTDKGRQKIVSLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERIYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G16E, L19I, E35D, M36I, R41K, D60E, I66V, H69K, L89M, I93L |
| >04PS194MB1| codons 1-99 PQITLWQRPLVTIKVEGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEVCGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6E, K14R, S17N, D25E, V31I, L45Q, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, A265V, D278A | S283G |
| >04PS194MB1| codons 1-288 FLDGIEKAQEEHERYHNNWRAMASEFNLPPIVAKEIVASCDKCQQKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |