Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt143 | 04PS169MB1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, M36L, N37S, R41K, L63P, H69K, V77I, L89M, I93L |
| >04PS169MB1| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P14S, V35T, E36A, T39E, S48T, D123E, K173A, N175Y, D177E, T200A, Q207E, R211K, V245Q, D250E, T286A, E291D, V292I, I293V, E297G, I329L, Q334C, G335D, R356K, G359N, T377M, K390R, A400T, E404D, E413D, L452I, R461K, V466I, S468T, T470S, D471E, H483Q, L491P, S519N, A534S, A554K |
| >04PS169MB1| codons 1-560 PISPIETVPVKLKSGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQYPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTGEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGCDQWTYQIYQEPFKNLKTGKYAKMRNA HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTDKGRQKIVTLSETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50I, F100Y, L101I, T112V, T124N, T125A, K136Q, V150I, V201I, T218I, L234I, A265V, R269K, D278A | S283G |
| >04PS169MB1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSNAVKAACWWAGIQQEFGIPYNPQSQGIVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |