Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt140 | 04PS161B1 | South Africa | 2004 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, K20R, E35D, M36I, P39S, R41K, K45R, Q61E, L63A, C67F, H69K, L89M, I93L |
| >04PS161B1| codons 1-99 PQITLWQRPLVSIKVGGQVREALLDTGADDTVLEDINLSGKWKPRMIGGIGGFIKVRQYD EIAIEIFGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, T39N, V60I, D123E, K166R, K173A, Q174K, D177E, G196E, T200A, I202V, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, P294A, Q334H, R356K, G359T, T369V, T377I, K390R, E399D, A400I, E404D, E432D, L452M, R461K, V466I, S468T, D471E, H483Q, L491S, S519N, Q520N, K527N, K530R, A554R |
| >04PS161B1| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIEQHRAKVEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVALTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLVEAVQKIAIESIVIWGKTPKFRLPIQKETWDIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKMGKAGYVTDKGRQKIVTLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNNIIEQLINKERVYLAWVPAHK GIGGNEQVDKLVSRGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E92G | K14R, D25E, V31I, I60M, L101I, K111Q, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A | S283G |
| >04PS161B1| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGM WQLDCTHLEGKIILVAVHVASGYIEAEVIPAGTGQETAYFILKLAGRWPVQVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |