<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt135 03SK232B1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, S48T, V60I, V118I, K122E, D123S, S134R, I135T, E138A, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T362N, T369A, A376T, T377M, K390R, E396D, A400T, T403A, E404D, V435I, R461K, D471E, T477A, Q480I, H483R, K530R, V531I, A534S, A554S H96R
>03SK232B1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPRPAGLKKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPRTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPELVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HNNDVKQLAEAVQKITMESIVIWGKTPKFRLPIQKDTWETWWADYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKAELI
AIRLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKERIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, K20R, M36I, R41K, H69K, L89M, I93L  
>03SK232B1| codons 1-99
PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006