<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt121 03SK107B1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10M, T12S, I15V, L19I, M36I, P39S, R41K, K45R, Y59C, H69K, L89M, I93L  
>03SK107B1| codons 1-99
PQITLWQRPMVSIKVGGQIKEALLDTGADDTVLEEINLSGKWKPRMIGGIGGFIKVRQCD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, D177E, T200E, E204K, Q207E, V245E, K277R, T286A, E291D, V292I, I293V, S322A, D324E, G335D, N348S, R356K, M357R, G359T, T377M, K390R, A400T, E404D, I434M, V435A, A437V, L452I, V467I, S468T, D471E, H483Q, L491S, I495V, K512R, S519N, Q524E, K530R, A534S, A554S K30E
>03SK107B1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEEIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHREKIEKLREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPAKELIAEIQKQGQDQWTYQIYQEPFKSLKTGKYAKRRTA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPMAGVETFYVDGAANRETKIGKAGYVTDRGRQKVITLTETTNQKTELQ
AIQLALQDSGSEVNVVTDSQYALGIIQAQPDRSESELVNQIIEELIKKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006