Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt117 | 03SK097B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19T, M36I, R41K, D60E, L63S, H69K, I93L |
| >03SK097B1| codons 1-99 PQITLWQRPLVTIKIGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QISIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I5V, V35T, E36A, T39D, S48T, K122E, D123G, T165I, K173A, Q174K, D177E, G196E, T200A, I202V, Q207E, V245Q, D250E, A272P, E291D, V292I, I293V, V317A, Q334D, R356K, G359T, K366R, A376S, T377M, K390R, A400T, T403S, E404D, V435A, A437V, K451R, L452I, V467I, D471E, H483Q, L491S, L517I, S519N, K530R, A534S, A554S | R78K, Q222R |
| >03SK097B1| codons 1-560 PISPVETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFKELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAKNPEIVI YQYMDDLYVGSDLEIEQHRAKVEELREHLLRWGFTTPDKKHRKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKISMESIVIWGKTPKFRLPIQKETWETWWSDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGVETFYVDGAANRETRIGKAGYVTDRGRQKVISLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50T, I72V, F100C, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, D207G, T218I, L234I, A265V, R269K, D278A | S283G |
| >03SK097B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYCILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATGIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |