Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt102 | 03SK062B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, N37K, R41I, L63S, H69K, V77I, L89M, I93L |
| >03SK062B1| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEMKLPGIWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123G, K173A, Q174K, T200A, Q207K, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329L, G335D, R356K, G359T, T377L, K390R, A400T, W406*, V435A, E449D, L452K, V466I, V467I, S468H, T470N, D471E, H483Q, L491S, E492V, S519N, Q524E, K530R, A534S, A554S |
| >03SK062B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTEY*QATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRDTKKGKAGYVTDRGRQKIIHLNETTNQKTELQ AIQLALQDSGSVVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, D25E, V31I, M50I, I72V, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, S255G, A265V, R269K, D278A | S283G |
| >03SK062B1| codons 1-288 FLDGIDKAQDEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNGDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |