Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt77 | 03PS152MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, G16A, L19I, M36I, R41K, F53Y, H69K, V82I, L89M, I93L |
| >03PS152MB1| codons 1-99 PQITLWQRPLVSIKIAGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGYIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V21I, V35T, E36A, T39E, E40D, V60I, W88C, K102R, V118I, K122E, D123G, I142T, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, R356K, G359T, A360T, T369A, T377L, K390R, A400I, E404D, N418S, V435A, L452M, K465E, V466I, S468P, D471E, L491S, I506L, S519N, K530R, A534S, A554K | E449K |
| >03PS152MB1| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTAICEDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKRKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRTT HTNDVKQLAEAVQKIALESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVSTP PLVKLWYQLEKEPIAGAETFYVDGAANRKTKMGKAGYVTDRGRQEIVPLTETTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGILQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, D25E, V31I, K34R, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167G, V201I, K211R, T218I, L234I, A265V, D278A | H16R, S283G |
| >03PS152MB1| codons 1-288 FLDGIDKAQEEHERYRSNWRAMASEFNLPPIVAREIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRGQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |