Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt75 | 03PS143MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, L63H, H69K, L89M, I93L |
| >03PS143MB1| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIHIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, E36A, T39E, S48T, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245R, A272P, K277R, V292I, I293V, E297A, V317A, I329V, Q334Y, G335D, R356K, G359T, T377L, K390R, A400I, E404D, V435I, L452I, V466I, D471E, T477A, H483Q, L491S, E492G, S519N, K530R, A534S, A554S |
| >03PS143MB1| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIRLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEIVPLTAEAE LELAENREILKEPVHGAYYDPSKDLIAEVQKQGYDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKIGKAGYVTDRGRQKIVSLTETTNQKAELQ AIQLALQDSGSGVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |