Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt70 | 03PS130MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, V82I, L89M, I93L |
| >03PS130MB1| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11Q, V35T, T39E, S48T, S68G, V90I, K122E, D123G, K166R, K173T, D177E, T200A, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, I293V, E297K, G335D, R356K, G359T, K366R, T377Q, K390R, A400T, E404D, V435I, K454R, K465R, D471E, Q480H, I482V, H483Q, L491S, A502V, S519N, K527Q, K530R, A534S, A554S | E79G |
| >03PS130MB1| codons 1-560 PISPIETVPVQLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDGTKWRKLVDFRGLNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGRAGYVTDRGRQRVVSLTETTNQKTELH AVQLALQDSGSEVNIVTDSQYVLGIIQAQPDKSESELVNQIIEQLIQKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, R20K, D25E, V31I, M50I, L101I, T112V, T124A, T125A, K136Q, G193E, V201I, T218I, L234I, A265V, R269K, D278A | S283G |
| >03PS130MB1| codons 1-288 FLDGIDKAQEDHERYHSNWKAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGEYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |