Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt60 | 03PS113MB2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, L19I, E35D, M36I, R41K, R57K, L63V, H69K, T74S, L89M, I93L |
| >03PS113MB2| codons 1-99 PQITLWQRPLVSVKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K102R, K122E, D123N, K166R, K173A, D177E, T200A, Q207K, V245Q, E248T, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334N, R356K, G359T, A371V, T377M, K390R, A400T, E404D, E432D, N447S, L452M, R461K, V466I, S468H, D471E, H483Q, L491P, Q507H, K527G, K530R, A534S, V548I, A554S | K11M |
| >03PS113MB2| codons 1-560 PISPIETVPVMLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPTKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEVVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKMGKAGYVTDKGRQKIVHLTETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIHAQPDKSESELVSQIIEQLIGKERVYLSWVPAHK GIGGNEQIDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, V31I, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, L234I, A265V, R269K, D278A | S283G |
| >03PS113MB2| codons 1-288 FLDGIDKAQDEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |