Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt44 | 03PS083MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I15V, L19V, M36I, R41K, L63T, H69K, V82I, L89M, I93L |
| >03PS083MB1| codons 1-99 PQITLWQRPLVAIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V8I, V35K, T39E, S48T, K122E, K126R, K173A, Q197K, T200E, R211K, V245Q, A272P, K277R, T286V, E291D, V292I, I293V, Q334H, G335E, R356K, G359T, T369A, T377M, K390R, A400I, T403I, E404D, V435I, A437V, G444E, L452M, Y457H, V458I, S468T, D471E, Q480K, H483Q, L491S, S515P, S519N, K530R, A534S, A554S |
| >03PS083MB1| codons 1-560 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRRYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIVI YQYMDDLYVGSDLEIGKHREKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGVKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHEQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKETWEIWWIDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGVETFYVDEAANRETKMGKAGHITDRGRQKVVTLTETTNQKTELK AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSEPELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, S24N, D25E, M50I, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, D278A | S283G |
| >03PS083MB1| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMANEFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGPN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |