<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt43 03PS081MB1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, M36L, N37A, H69K, L89M, I93L  
>03PS081MB1| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEELALPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, S48T, V60I, K122E, D123S, A158S, K173A, Q174K, D177E, I195T, T200A, Q207K, R211S, F214L, V245Q, A272P, Q278K, T286A, E291D, V292I, I293V, Q334D, G335D, T338S, R356K, G359T, K366R, T377L, K390R, A400T, E404D, V435A, L452R, D460G, V466I, T470S, D471E, H483Q, L491T, S519N, K530G, A534S, A554S F130S
>03PS081MB1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTASTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLETGQHRAKIEELRKHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKKLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWSYQIYQEPFKNLKTGKYAKMRTA
HTNDVRQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKRGKAGYVTGRGRQKIVSLSETTNQKTELQ
AIQLALQDSGTEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEGVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006