Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt41 | 03PS077B1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, V60I, V90I, V118I, K122E, T139K, I142K, T165I, K173A, I202V, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, L325S, Q334E, R356K, G359T, T377L, K390R, A400T, E404D, V435A, G436E, N447S, L452Q, V466I, V467I, S468P, D471E, T477A, H483R, L491S, S519N, Q520K, K527E, K530R, A534S, A554S |
| >03PS077B1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNEKPGKRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAQNPDIVI YQYMDDLYVGSDLEIGQHRTKVEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDSIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAASRETKQGKAGYVTDRGRQKIIPLTETTNQKAELQ AIRLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNKIIEQLIEKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, E35D, M36I, R41K, R57K, D60E, H69K, V82I, L89M, I93L |
| >03PS077B1| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24C, D25E, V31I, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, K188R, V201I, T218I, L234I, A265V, R269K, D278A | S283G |
| >03PS077B1| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMACEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRRGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |