Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt37 | 03PS067MB2 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, K70R, V82I, L89M, I93L |
| >03PS067MB2| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYE EIPIEICGKRAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K104R, V118I, K122E, D123N, E138A, R172K, K173I, Q174K, T200A, E204K, Q207D, R211K, F214L, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, P313Q, V317A, I326V, Q334C, G335D, R356K, G359T, A371T, T377L, K390R, E399G, A400T, E404D, P420L, V435A, A437V, L452K, V466I, S468P, D471E, T477A, H483Q, L491P, S519N, K527N, K530R, V531I, A534S, A554S |
| >03PS067MB2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSIPL DENFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEKLRDHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEQVHGAYYDPSKDLVAEIQKQGCDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTETVQKIALESIVIWGKTPKFRLPIQKETWGTWWTDYWQATWIPEWEFVNTL PLVKLWYQLEKEPIAGVETFYVDGAANRETKKGKAGYVTDRGRQKIVPLTETTNQKAELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, S24N, D25E, V31I, M50I, I60V, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, R269K, D278T | S283G |
| >03PS067MB2| codons 1-288 FLDGIDKAQEDHERYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGV WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGTDCVAGRQDED |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |