Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt26 | 03PS049MB1 | South Africa | 2003 | HIV1 | C | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, E35D, M36I, N37D, H69K, V82I, L89M, I93L |
| >03PS049MB1| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, K102R, K122E, K173T, Q174K, D177E, T200A, Q207A, V245Q, A272P, K275Q, R284K, E291D, V292I, I293V, E328D, G335D, R356K, M357R, G359T, K366R, T377M, K390R, A400T, E404D, I411V, I434L, V435T, A437V, L452M, V466I, S468T, L469I, H483Q, L491P, K530R, A534S, A554S |
| >03PS049MB1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLKGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIADIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVRQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWVPEWEFVNTP PLVKLWYQLEKEPLTGVETFYVDGAANRETKMGKAGYVTDRGRQKIVTITDTTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |