<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt26 03PS049MB1 South Africa 2003 HIV1 C Plasma MC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, E35D, M36I, N37D, H69K, V82I, L89M, I93L  
>03PS049MB1| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, S48T, K102R, K122E, K173T, Q174K, D177E, T200A, Q207A, V245Q, A272P, K275Q, R284K, E291D, V292I, I293V, E328D, G335D, R356K, M357R, G359T, K366R, T377M, K390R, A400T, E404D, I411V, I434L, V435T, A437V, L452M, V466I, S468T, L469I, H483Q, L491P, K530R, A534S, A554S  
>03PS049MB1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLKGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIADIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDVRQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWVPEWEFVNTP
PLVKLWYQLEKEPLTGVETFYVDGAANRETKMGKAGYVTDRGRQKIVTITDTTNQKTELQ
AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rousseau, CM Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. J Virol Methods, 2006