<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV_02CM-CK1_2 02CM-2 Cameroon 2002 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, R41K, R57RK, D60E, L63P, H69C  
>02CM-2| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QIPIEICGCKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K22R, V35T, K49R, V60I, V106I, I135V, T139A, T165I, E169D, D177E, I178L, Q207E, F214FL, V245T, D250E, S251D, A272P, T286A, E297Q, K311R, I329V, Q334CS, T338S, Y339W, R356RK, E370D, A376AS, T377Q, S379C, K390R, T403M, E404D  
>02CM-2| codons 1-430
PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNEAPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRKQNPELVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTQEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGSGQWSWQIYQEPFKNLKTGKYAKMRGA
HTNDVKQLTDAVQKISQECIVIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP
PLVKLWYQLE

References
Author Title Citation
Vergne, L Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients. J Clin Virol, 2006