<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AIO_DDJ172 AIO_DDJ172 Nigeria 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, R41K, C67S, H69R, V77I, V82I, L89M  
>AIO_DDJ172| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGRKAIGTVLIGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, I31V, V35T, T39K, K46R, V60I, D121Y, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251V, A272P, I274V, Q278H, K281R, T286A, E291D, V292I, P294T, E297T, L301M, I329V, Q334P, G335D, F346Y, Y354F, R356K, M357R, R358G, G359S, A371V, S379G, T386I, Q394R, A400V, K431T, V435L, F440Y G231R
>AIO_DDJ172| codons 1-440
PISPIETVPVKLKPGMDGPRVKQWPLTEEKVKALTEICKEMEKEGRISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMRYELHPDKWT
VQPIQLPDKEVWTVNDIQKLVGKLNWASQIYPGVKVKHLCRLLRGAKALTDIITLTTEAE
MELAENREILKEPVHGVYYDPSKDLIAEVQKQGPDQWTYQIYQEPYKNLKTGKFAKRGSA
HTNDVKQLTEVVQKIATEGIVIWGKIPKFKLPIRKETWEVWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPILGAETY

References
Author Title Citation
Ojesina, AI Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response. ARHR, 2006