<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AIO_DDJ150 AIO_DDJ150 Nigeria 2003 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K14R, L19P, K20I, E35K, M36I, R41K, Q61H, H69K, L89M, C95V  
>AIO_DDJ150| codons 1-99
PQITLWQRPVVTVRIGGQPIEALLDTGADDTVLEKINLPGKWKPKMIGGIGGFIKVRQYD
HILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGVTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    P236L   V35T, E36D, V60I, I135V, N147D, S162A, P170S, K173A, Q174K, D177E, T200E, Q207E, V245Q, E248D, S251C, K277R, T286A, E291D, V292I, I293V, S322T, D324E, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, A400T, T403M, K431R, E432D, V435A V111E
>AIO_DDJ150| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDEGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYDVLPQGWKGSPAIFQASMTKILESFRAKNPEIVI
YQYMDDLYVGSDLEIGQHREKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHLDKWT
VQPIQLPDKDCWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVATEGIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLERDPIAGAETF

References
Author Title Citation
Ojesina, AI Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response. ARHR, 2006