<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AIO_DDJ137 AIO_DDJ137 Nigeria 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M  
>AIO_DDJ137| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39M, V60I, K122E, D123S, I135T, K173T, Q174N, D177E, I195T, T200A, Q207E, V245R, E248D, D250E, A272P, T286A, E291D, I293V, P294T, I329V, Q334R, G335D, F346Y, R356K, M357R, R358G, G359S, S379G, V381I, T386V, Q394R, E399D, A400V, K431T, V435L, F440Y  
>AIO_DDJ137| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTNNPEIVI
YQYMDDLYVGSDLETGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIRLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGRDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEAVQKIATEGIIIWGKVPKFKLPIRKETWDVWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPILGAETY

References
Author Title Citation
Ojesina, AI Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response. ARHR, 2006