Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AIO_DDJ135 | AIO_DDJ135 | Nigeria | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, L19I, K20I, E35D, M36I, R41K, R57K, L63P, C67E, H69K, L89M |
| >AIO_DDJ135| codons 1-99 PQITLWQRPLVTVRIGGQIIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIPIEIEGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, D123N, I135V, I142V, Q174R, D177E, I178M, T200A, Q207D, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, D324E, I329V, Q334L, G335D, F346Y, R356K, M357K, R358G, G359S, K366R, T377I, T386I, Q394R, A400V, E413D, Q428R, K431T, V435P, F440Y | R78K |
| >AIO_DDJ135| codons 1-440 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFKELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKKGSA HTNDVRQLTEAVQKIAIESIVIWGKIPKFKLPIRKETWEVWWTEYWQATWIPDWEFVNTP PLVKLWYRLETEPIPGAETY |
References
| Author | Title | Citation |
| Ojesina, AI | Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: implications for drug resistance and host response. | ARHR, 2006 |