<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AIO_DDJ134 AIO_DDJ134 Nigeria 2003 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, E35D, M36I, R41K, R57K, L63I, H69K, L89M  
>AIO_DDJ134| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y188H   V35T, E36D, E40D, K49R, V60I, K122E, A158S, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, K275R, Q278H, L282C, L283I, I293V, A327V, G335D, P345Q, F346Y, R356K, A360T, T377Q, K390R, A400T, A408V, E432D  
>AIO_DDJ134| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPEMVI
YQYMDDLHVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIRVKHLCKCIRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQDQWTYQIYQEQYKNLKTGKYAKMRGT
HTNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWETWWTEYWQVTWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETF

References
Author Title Citation
Ojesina, AI Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response. ARHR, 2006