<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AIO_DDJ128 AIO_DDJ128 Nigeria 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69R, I72V, V82I, L89M, I93V  
>AIO_DDJ128| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQIDLPGKWKPKMIGGIGGFIKVKQYD
QIPIEIEGRKAVGTVLVGPTPINIIGRNMLTQVGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, V60I, K102R, K173A, Q174R, D177E, I178M, T200V, Q207D, R211K, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, D324E, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, T377L, V381I, T386V, K390R, Q394R, A400V, E413D, K431T, V435A, F440Y H208Q
>AIO_DDJ128| codons 1-440
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEMVI
YQYMDDLYVGSDLEIGQHRVKIEELRDQLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVRQLTEAVQKIALESIIIWGKVPKFRLPIRKETWEVWWTEYWQATWIPDWEFVNTP
PLVKLWYQLETEPIAGAETY

References
Author Title Citation
Ojesina, AI Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response. ARHR, 2006